Endocrine Abstracts

Introduction: Classification of diabetes is challenging in some cases, especially in the presence of inaugural ketosis with a negative autoimmune laboratory test. The aim of our study is to determine the role of age, body mass index (BMI), and fasting plasma C-peptide (FCP) in the classification of diabetes.Methods: This is a descriptive cross-sectional study that included 51 patients aged between 20 and 65 years hospitalized at the Endocrinology Departm...

Introduction: Papillary Thyroid Carcinoma (PTC) is the most frequent cancer of the thyroid. PTC may rarely coexist with Primary hyperparathyroidism (PHPT). Furthermore, the association of PTC and graves’ disease (GD) has been described and the existence of a link between these entities has long been investigated, but no clear correlation has been established. We report the case of a female patient who suffered from GD, PTC and PHPT.Observation: A 34...

Introduction: Papillary thyroid carcinoma is one of the most prevalent endocrine tumors. Adrenocorticotropic hormone (ACTH) dependent Cushing’s syndrome is a rare disease. We report a rare case of coexistence of papillary thyroid carcinoma and ACTH-dependent Cushing’s syndrome.Observation: A 59-year-old man, was admitted to our endocrinology department for exploration of bilateral adrenal incidentalomas discovered in an abdominal CT scan done i...

Introduction: Adrenal adenomas development has been partially explained by aberrant adrenal expression of some hormone receptors. Klinefelter’s syndrome is a common cause of hypergonadotropic hypogonadism, which is characterized by increased serum LH level. In this case, we report a patient with Klinefelter syndrome, who was later diagnosed with a non secreting adrenal adenoma.Case presentation: We report the case of a 57 years old patient, diagnose...

Introduction: Gilbert syndrome is a common autosomal dominant hereditary condition characterized by intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or hemolysis. Multiple endocrine neoplasia (MEN) is defined by the association of a neoplasia or hyperplasia of at least two endocrine glands and caused by multiple mutations. Rare cases of atypical MEN were reported in the literature. We report the case of a patient with a history of gilbert&#...

Introduction: Liraglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA), approved for management of type 2 diabetes (T2D).Aim: The aim of our study is to evaluate the effectiveness of Liraglutide in controlling blood glucose levels over a period of 6 to 12 months in Tunisian type 2 diabetic patients.Methods: We conducted a prospective descriptive study at the endocrinology-nutrition department of the military hospital of...

Introduction: Liraglutide has been shown to have a positive effect on the glycemic and lipidic profile of diabetic patients. We aimed to assess the metabolic profile in type 2 diabetic patients after 12 weeks of treatment by LiraglutideMethods: This is a prospective study performed at the endocrinology department of the Military Hospital of Tunis. We recruited 22 patients with type 2 diabetes (T2D) treated with insulin and/or oral antidiabetics. Liraglut...

Introduction: Glycemic control and weight management are crucial considerations in the treatment of type 2 diabetes (T2D). Liraglutide, an incretin-based therapy, has been demonstrated to not only effectively maintain glycemic control but also promote weight loss in type 2 diabetic patients. Our study aims to evaluate the impact of Liraglutide on body weight and body composition parameters in patients with T2D.Methods: This is a prospective study, carrie...

Introduction: Liraglutide is an anti-diabetic drug that has been shown to be effective for glycemic control and weight loss. However, factors such as unavailability, high cost, and side effects may make it challenging for patients to continue treatment. Our study aims to identify these barriers to treatment adherence and to understand the factors contributing to the discontinuation of Liraglutide therapy in Tunisian patients with type 2 diabetes (T2D).Me...

Introduction: Gelastic seizures have been typically described with hypothalamic hamartomas and precocious puberty. Invasive EEG recordings have shown that gelastic seizures originated from the hypothalamic hamartomas, however recent findings have shown that they might also arise from other central lesions, like tumors, malformations of cortical development, postinfectious foci and other hypotalamic or pituitary abnormalities. In this case, we describe a patient with gelastic s...